venofer dosing calculator

A target haemoglobin value is also input so iron deficit can be determined according to a specified individual target. Applies only to oral form of both agents. Applies only to oral form of both agents. Minor/Significance Unknown. Intravenous (IV) iron products (use in adults) Dosing information in this table is for adults and includes some dosing recommendations not listed in the approved product information. Monitor Closely (1)iron sucrose decreases levels of liothyronine by inhibition of GI absorption. Monitor Closely (1)esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. iron sucrose increases levels of calcium gluconate by enhancing GI absorption. Minor/Significance Unknown. Next Steps Evidence Creator Insights Dr. Andreas M. Ganzoni About the Creator Adult Dosage and Administration: The recommended dosage of Ferrlecit for the repletion treatment of iron deficiency in hemodialysis patients is 10 mL of Ferrlecit (125 mg of elemental iron). Dose administration to an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal or cardiac function, and of concomitant disease or other drug therapy. Comparable efficacy to that of IV iron sucrose. This cost includes the fee charged by the pharmacy. Venofer must only be administered intravenously either by slow injection or by infusion. The plasma ferritin level as a reliable index of body iron stores following intravenous iron dextran. Adverse pregnancy outcomes associated with IDA include increased risk for preterm delivery and low birth weight. By taking into account the case of a patient weighing 78 kg (172 lbs) and having a hemoglobin level of 11 g/dL (110 g/L or 6.83 mmol/L). Multiple placebo-controlled, randomized clinical trials have been conducted with IV iron in patients with New York Heart Association class II-III heart failure with an ejection fraction 45% who met criteria . Anemia of chronic disease (ACD), Calculation of the Total Iron Deficit equation appears in Cosmofer PI, Calculation of the Total Iron Deficit Alternative equation, Iron Dextran Dosing Calculator (iron deficit), HONcode standard for trust- worthy health, Pediatric Oncology: Diagnosis And Prognosis Communication, Pharmacosmos A/S, CosmoFer low molecular weight (Mw) iron dextran. Avoid or Use Alternate Drug. 3) Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. (1988) Clinical use of the total dose intravenous infusion of iron dextran. When to Use Weight lbs Target hemoglobin g/dL Actual hemoglobin g/dL Iron stores Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg mg Result: Please fill out required fields. Dosage: For patients weighing 50 kg (110 lb) or more: Give Injectafer in two doses separated by at least 7 days. Modify Therapy/Monitor Closely. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or iron sucrose decreases levels of eltrombopag by inhibition of GI absorption. Use Caution/Monitor. Minor (1)iron sucrose, benazepril. [. Available for Android and iOS devices. This information does not assure that this product is safe, effective, or appropriate for you. Applies only to oral form of both agents. J Med. Modify Therapy/Monitor Closely. Use Caution/Monitor. Avoid or Use Alternate Drug. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. Patients may present with shock, clinically significant hypotension, loss of consciousness and/or collapse. This drug is available at a higher level co-pay. If either is present, do not use the liquid. Applies only to oral form of both agents. The iron deficit calculator is useful as one of the determinations performed before iron replenishment therapy is initiated. Minor/Significance Unknown. There is in depth information below the form on the method used and on the result provided. Serious - Use Alternative (1)iron sucrose decreases levels of levofloxacin by inhibition of GI absorption. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. Avoid or Use Alternate Drug. Fill in the calculator/tool with your values and/or your answer choices and press Calculate. Parenteral iron supplementation. Use Caution/Monitor. Step 2: Calculation and administration of the maximum individual iron dose(s): . Share cases and questions with Physicians on Medscape consult. Most Assure stable intravenous access to avoid extravasation. Studies in monkeys showed concurrent use with calcium, aluminum, or iron caused significantly decreased plasma levels. Use Caution/Monitor. calcium chloride decreases levels of iron sucrose by inhibition of GI absorption. Minor/Significance Unknown.iron sucrose increases levels of calcium gluconate by enhancing GI absorption. Each mL contains 20 mg of elemental iron. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Intermediate calculations: -Blood volume (dL) = [65 (mL/kg) x body weight (kg)] / 100 (mL/dL) -Hgb deficit (g/dL) = 14.0 - patient hemoglobin conc. Administer Venofer early during the dialysis session (generally within the first hour). The dosing for iron replacement treatment in pediatric patients with HDD-CKD has not been established. esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Kumpf VJ, Holland EG. lansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. The dosage of Venofer is expressed in mg of elemental iron. Use Caution/Monitor. . Talk to your pharmacist for more details.During pregnancy, this medication should be used only when clearly needed. Oral and parenteral products - see background option for oral products. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Parenteral Iron Replacement For Iron Deficiency Anemia Calculator, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Clinical use of the total dose intravenous infusion of iron dextran, When is high-dose intravenous iron repletion needed? Minor/Significance Unknown. Oral iron therapy is the first method while IV therapy comes in place when there are contraindications or the body doesnt respond to the oral one. Monitor Closely (1)dexlansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. (See also Notes section. Applies only to oral form of both agents. All Rights Reserved. Applies only to oral form of both agents. Deferiprone may bind polyvalent cations (eg, iron, aluminum, and zinc), separate administration by at least 4 hr between deferiprone and other medications (eg, antacids), or supplements containing these polyvalent cations. We first individually analyzed 5 clinical studies, averaging the total iron deficit across all patients utilizing a . Do Not Copy, Distribute or otherwise Disseminate without express permission. Do not mix iron sucrose with other medications or TPN solution. Serious - Use Alternative (1)iron sucrose decreases levels of mycophenolate by inhibition of GI absorption. iron sucrose decreases levels of minocycline by inhibition of GI absorption. Use Caution/Monitor. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Deferoxamine chelates iron. Slow or stop the infusion if adverse reactions occur. Fatal reactions have also occurred in situations where the test dose was tolerated. Evaluate the hematologic response (hemoglobin, ferritin, iron and transferrin saturation) at least one month following the second Feraheme infusion. We'll do this entirely for free, as long as the calculator has applications for women's health. aluminum hydroxide will decrease the level or effect of iron sucrose by increasing gastric pH. Ren Fail. This parenteral iron replacement for iron deficiency anemia calculator determines the parenteral dose of iron supplement needed to replenish iron stores and hemoglobin levels. The recipient will receive more details and instructions to access this offer. When iron sucrose was administered at deliberate overdoses to rabbit dams (up to 215 mg/kg/day) marked fetal/placental iron overload was noted. Monitor patients for signs and symptoms of hypersensitivity during and after Venofer administration for at least 30 minutes and until clinically stable following completion of the infusion. Minor/Significance Unknown. This health tool computes the iron deficit based on patient parameters and the Ganzoni formula. Deferasirox chelates iron. 4. Applies only to oral form of both agents. Am J HealthSyst Pharm 2006;63:731735. with NDD-CKD or PDD-CKD who are on erythropoietin therapy for iron maintenance treatment, Hemodialysis-dependent chronic kidney disease (HDD-CKD)*, Non-dialysis-dependent chronic kidney disease (NDD-CKD), Peritoneal-dialysis-dependent chronic kidney disease (PDD-CKD), At a dose of 0.5 mg/kg, not to exceed 100 mg per dose, Given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at concentrations of 1 to 2 mg/mL and administered over 5 to 60 minutes, An increase in Hb concentration or a decrease in ESA dose is desired and. Applies only to oral form of both agents. Controlled studies in pregnant women show no evidence of fetal risk. DOSAGE AND ADMINISTRATION: The recommended dose of Feraheme is an initial 510 mg dose followed by a second 510 mg dose 3 to 8 days later. Administer Venofer early during the dialysis session (generally within the first hour). Venofer has not been studied in patients younger than 2 years old. Divide the calculated dose by the patient's weight (IBW if BMI >30, or actual body weight (ABW) if BMI30) to ensure it does NOT exceed 20mg/kg. Anemia; 2015: 763576. INFED- iron dextran injection [Package insert], Hemoglobin iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) Note: Hbg (current hemoglobin level) units: (g/dL) Alternatively: Volume of product required (mL) = [weight (kg) x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. Serious - Use Alternative (1)iron sucrose decreases levels of ofloxacin by inhibition of GI absorption. The usual total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. May increase risk of hypotension. Applies only to oral form of both agents. Schweiz Med Wochenschr. iron sucrose decreases levels of fleroxacin by inhibition of GI absorption. Monitor Closely (1)iron sucrose decreases levels of penicillamine by inhibition of GI absorption. Applies only to oral form of both agents. We comply with the HONcode standard for trustworthy health information. ONE DOSE. Use Caution/Monitor. Ferrlecit has been administered at sequential dialysis sessions by infusion or by slow intravenous injection during the dialysis session itself. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Applies only to oral form of both agents. A patients lean body weight (or actual body weight if less than lean body weight) should be utilized when determining dosage. Use Caution/Monitor. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. Most studies have used IV iron sucrose (maximum dose of 200 mg per setting) or ferric carboxymaltose (maximum dose of 1000 mg per week). Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Applies only to oral form of both agents. Iron deficiency anemia calculator (diagnosis), Iron deficiency anemia vs. iron sucrose increases levels of calcium citrate by enhancing GI absorption. Hypotension following administration of Venofer may be related to rate of administration and/or total dose delivered. iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. Minor/Significance Unknown. All adult and pediatric patients receiving Venofer require periodic monitoring of hematologic and iron parameters (hemoglobin, hematocrit, serum ferritin and transferrin saturation). Recommended Treatment Regimen Using IV Iron Sucrose for Initial Repletion in Children With Iron Deficiency Anemia. After total replacement dose completed, need for ongoing IV doses should be re-assessed monthly. Bhowmik D, Modi G, Ray D, Gupta S, Agarwal SK, Tiwari SC, Dash SC. Modify Therapy/Monitor Closely. 2) Koch TA, Myers J, Goodnough LT. (2015) Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. vonoprazan will decrease the level or effect of iron sucrose by inhibition of GI absorption. Separate dosing of tetracyclines from these products. 1974 Jun;31(6):592-5. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Am J Hosp Pharm. Observed Hb = the patients current hemoglobin in g/dl. Drug: Comments: A: Acyclovir 1: Dose using a 40% adjusted body weight; Amikacin 2: Dose using a 40% adjusted body weight; Amphotericin B (liposomal) 3 Consider capping body weight to 100 kg; Atracurium 4: Dose using ideal body weight; The use of ideal body weight has been shown to be associated with a more predictable muscle strength recovery within 60 minutes and a lack of need for antagonism . Use Caution/Monitor. Applies only to oral form of both agents. Minor (2)calcium chloride decreases levels of iron sucrose by inhibition of GI absorption. Excessive dosages of Venofer may lead to accumulation of iron in storage sites potentially leading to hemosiderosis. Do not dilute to concentrations below 1 mg/mL [see How Supplied/Storage and Handling (16.2).] Brand name: Venofer Drug class: Iron Preparations Chemical name: iron saccharate CAS number: 8047-67-4 Medically reviewed by Drugs.com on Oct 25, 2022. Applies only to oral form of both agents. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=abacb7fa-2fc2-471e-9200-944eeac8ca2a. When administering as a slow intravenous push, give at the rate of approximately 100 mg (2 mL) per minute. Recommended starting dose 1 Aranesp is dosed at 2.25 mcg/kg SC QW or 500 SC Q3W 1 (SC = subcutaneous) Before initiating 1: Evaluate iron status; administer supplemental iron therapy as needed Correct or eliminate other causes of anemia Initiate 1: Only when Hb < 10 g/dL Applies only to oral form of both agents. The iron deficit estimation is based on the Ganzoni formula: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores. Applies only to oral form of both agents. May increase risk of hypotension. Your doctor will do laboratory tests to monitor your response. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. FERAHEME was non-inferior to Venofer (iron sucrose) in mean Hgb rise from baseline 2,5. The usual total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Serious hypersensitivity reactions, including anaphylactic-type reactions, some of which have been life-threatening and fatal, have been reported in patients receiving Venofer. Pain, swelling, or redness at the injection site may occur. DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. Consult your doctor before breast-feeding. Venofer (iron sucrose) dose calculator | Calculosaurus.com Clinical calculators for obstetrics and gynaecology VTE risk assessment Calculator menu Venofer dose calculator Iron sucrose Not what you were looking for? iron sucrose decreases levels of penicillamine by inhibition of GI absorption. Applies only to oral form of both agents. Many patients with kidney disease cannot get enough iron from food and require injections. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl [see How Supplied/Storage and Handling (16.2).] Monitor for signs and symptoms of hypotension following each Feraheme infusion. Applies only to oral form of both agents. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at a concentration of 1 to 2 mg/mL and administered over 5 to 60 minutes. Avoid or Use Alternate Drug. This website is intended for use by US healthcare professionals only. There is limited experience with administration of an infusion of 500 mg of Venofer, diluted in a maximum of 250 mL of 0.9% NaCl, over a period of 3.5 to 4 hours on Day 1 and Day 14 [see How Supplied/Storage and Handling (16.2). If we don't have the calculator you need we'll try to make it for you and add it to the website. It is unlikely . Use Caution/Monitor. Avoid or Use Alternate Drug. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. You are encouraged to report Adverse Drug Events to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. 4) Gozzard D. (2011) When is high-dose intravenous iron repletion needed? Applies only to oral form of both agents. For males: LBW = 50 kg + 2.3 kg for each inch of patients height over 5 feet For females: LBW = 45.5 kg + 2.3 kg for each inch of patients height over 5 feet Administration: I. For iron maintenance treatment, administer Venofer, (2 years of age or older) with NDD-CKD or PDD-CKD who are on erythropoietin therapy for iron maintenance treatment. Methods: We reviewed the experience of our department between January, 2011 and February, 2014 with the use of intravenous iron sucrose in children 14 years of age who failed in oral iron therapy for iron deficiency anemia (IDA). Intravenous iron-dextran: therapeutic and experimental possibilities, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Diagnosis and management of iron deficiency anaemia: a clinical update. Use Caution/Monitor. Applies only to oral form of both agents. Intravenous Injection - PRIOR TO THE FIRST INTRAVENOUS INFeD THERAPEUTIC DOSE, ADMINISTER AN INTRAVENOUS TEST DOSE OF 0.5 ML. Minor/Significance Unknown. Applies only to oral form of both agents. Monitor Closely (1)omeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. Applies only to oral form of both agents. Included in the iron dextran package insert. restrictions. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. Discard unused portion. Equations used: 1] Calculation of the Total Iron Deficit: Total iron deficit [mg] = body weight [kg] x (target Hb-actual Hb) [g/dl] x 2.4 + depot iron [mg]. INFeD is given undiluted at a slow gradual rate not to exceed 50 mg (1 mL) per minute. ]Venofer treatment may be repeated if iron deficiency reoccurs. deferasirox decreases levels of iron sucrose by inhibition of GI absorption. Max Dose. Applies only to oral form of both agents. In less advanced cases of iron deficiency, increases in dietary intake of iron may be sufficient. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. 0.5 mg/kg (not to exceed 100 mg/dose) diluted to a concentration of 1 to 2 mg/mL in 0.9% sodium chloride IV over 5 to 60 minutes Administer every 4 weeks for 12 weeks Do not dilute to concentrations below 1 mg/mL Comments: Treatment may be repeated if necessary. IMPORTANT SAFETY INFORMATION DOSAGE AND ADMINISTRATION Pediatric Patients (2 Years of Age and Older) iron sucrose, captopril. The primary endpoint was the proportion of patients with . Monitor Closely (1)trientine, iron sucrose. Below the form there are further instructions on how to use the calculator. Use Caution/Monitor. Use Caution/Monitor. Copyright 2021 GlobalRPH - Web Development by. Avoid or Use Alternate Drug. Dr. Ganzonis primary research is focused on iron deficiency and plasma iron transport. This calculator will help pinpoint potential causes of anemia based on Formula for calculating the required dose of iron sucrose 1. commonly, these are "non-preferred" brand drugs or specialty 1982;13(4):309-21. Applies only to oral form of both agents. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time.Your dosage and length of treatment are based on your medical condition, age, and response to treatment. prescription products. OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Read our. May increase risk of hypotension. Where: Medicine concentration Amount of active substance per a given volume of your drug. Use Caution/Monitor. HONcode standard for trust- worthy health, Pediatric Oncology: Diagnosis And Prognosis Communication. Drug class: Iron products. Calculation of Dosage of Nefrofer Total Iron Deficit (mg) Nefrofer (ml) = 20mg/ml Total Iron Deficit (mg) = Body weight (kg) x (Target Hb - Actual Hb) [g/l] x 0.24* + Depot Iron . * Calculators are available in UpToDate to determine ideal body weight and lean body weight. Indicated for treatment of iron deficiency anemia associated with chronic kidney disease, Hemodialysis-dependent CKD: 100 mg elemental iron IV (injection or infusion over 2-5 min) per dialysis session not to exceed total cumulative dose of 1000 mg divided in 3 doses/week, Non-dialysis-dependent CKD: 200 mg IV injection for 5 doses in over 14 days (cumulative 1000 mg in 14-day period), Peritoneal dialysis-dependent CKD: 300 mg IV infusion (1.5 hr) for 2 doses 14 days apart, THEN 400 mg IV infusion (2.5 hr) 14 days later (cumulative 1000 mg divided in 3 doses/week), Indicated for maintenance treatment of iron-deficient anemia associated with chronic kidney disease, <2 years: Safety and efficacy not established, Iron replacement treatment in pediatric patients has not been established. Either increases effects of the other by pharmacodynamic synergism. calcium citrate decreases levels of iron sucrose by inhibition of GI absorption. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Each mL contains 20 mg of elemental iron. Ferrlecit may also be administered undiluted as a slow intravenous injection (at a rate of up to 12.5 mg/min) per dialysis session. 1970; 100(7):301-3. Monitor Closely (1)nizatidine will decrease the level or effect of iron sucrose by increasing gastric pH. The incidence of adverse events with the 400- and 500-mg doses administered as a 2-hour . Interaction only with oral iron administration. Minor/Significance Unknown.iron sucrose increases levels of calcium chloride by enhancing GI absorption. Each mL contains 20 mg of elemental iron. For liquid medications, also enter the value of the Medicine Concentration and choose . Last updated 28/06/2018 Enter values here and press 'Calculate'. Hanson DB, Hendeles L. Guide to total dose intravenous iron dextran therapy. Modify Therapy/Monitor Closely. Jacobs P, Dommisse J. Intravenous iron-dextran: therapeutic and experimental possibilities [in German] Schweiz Med Wochenschr. Minor/Significance Unknown.iron sucrose increases levels of calcium carbonate by enhancing GI absorption. Hemoglobin iron deficit = 60 x (14 - 8) x (2.145) = 772 mg iron. Serious - Use Alternative (1)iron sucrose decreases levels of eltrombopag by inhibition of GI absorption. Use Caution/Monitor. Serious - Use Alternative (1)iron sucrose decreases levels of tetracycline by inhibition of GI absorption. By clicking send, you acknowledge that you have permission to email the recipient with this information. Applies only to oral form of both agents. omeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. Kumpf VJ. Iron Deficiency In Pregnancy Calculator, Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator. Chandler G, Harchowel J, Macdougall I. Fulminant symptoms include confusion, sensation of passing out, paleness. Applies only to oral form of both agents. 1. rabeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Maximum infusion rate: 100 mg / hour (Slow infusion rate of iron sucrose is recommended to minimize adverse reactions, especially hypotension) Frequency of infusion: Dose may be repeated up to 3 times weekly to provide total iron dose. Applies only to oral form of both agents. (2010) Diagnosis and management of iron deficiency anaemia: a clinical update. Severe adverse reactions including circulatory failure (severe hypotension, shock including in the context of anaphylactic reaction) may occur in pregnant women with parenteral iron products (such as Venofer) which may cause fetal bradycardia, especially during the second and third trimester. Intravenous therapy is usually recommended in case of contraindications to oral iron, comorbidities that prevent absorption, chronic renal impairment or iron replacement needs to be rapid. Applies only to oral form of both agents. Privacy Policy, Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg. Uses for Iron Sucrose This topic . The original formula employs the weight in kg but users can input it in lbs and it gets transformed. Applies only to oral form of both agents. IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. Properly discard this product when it is expired or no longer needed. Applies only to oral form of both agents. Interaction only with oral iron administration. Use Caution/Monitor. Applies only to oral form of both agents. Modify Therapy/Monitor Closely. The dosing for iron replacement treatment in pediatric patients with Peritoneal or Hemodialysis-Dependent - CKD or Non-Dialysis Dependent CKD have not been established. Minor/Significance Unknown. Applies only to oral form of both agents. Generic name: IRON SUCROSE 20mg in 1mL Where C= concentration of INDICATIONS AND USAGE: Intravenous or intramuscular injections of INFeD are indicated for treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. Parenteral iron product is iron sucrose (C = 20 mg elemental iron/mL). This site contains information for licensed healthcare professionals in the United States. Use Caution/Monitor. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Either decreases levels of the other by inhibition of GI absorption. Use Caution/Monitor. Copyright(c) 2023 First Databank, Inc. David McAuley, Pharm.D. Separate dosing of tetracyclines from these products. You may report side effects to Health Canada at 1-866-234-2345. Applies only to oral form of both agents. 20 mg/mL for Iron sucrose; 5 mg/mL for Ferric gluconate. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. calcium carbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Serious - Use Alternative (1)iron sucrose decreases levels of fleroxacin by inhibition of GI absorption. Iron Deficiency Anemia: Periodic hematologic determination (hemoglobin and hematocrit) is a simple and accurate technique for monitoring hematological response, and should be used as a guide in therapy. The following table present normal hemoglobin ranges: There is another equation for iron deficit that can be used to calculate replenishment needs, that of Ganzoni, which takes into account iron stores as well and that can be found in the iron deficit calculator. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Kidney Int. Hemoglobin can be input in g/dL, g/L or mmol/L and refers to the amount of hemoglobin in the red blood cells. Fatal reactions have followed the test dose of iron dextran injection. The dosage of Venofer is expressed in mg of elemental iron. Consult your doctor for more details.Remember that it is best to get your vitamins and minerals from food whenever possible. vitamin E decreases levels of iron sucrose by increasing hepatic clearance. Human studies not conducted. Anemias. Serious - Use Alternative (1)iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. The dose of Venofer must be individually calculated for each patient according to the total iron deficit calculated with the following Ganzoni formula, for example: Total iron deficit [mg] = BW [kg] x (target Hb - actual Hb) [g/dl] x 2.4* + storage iron [mg] Below 35 kg BW: 35 kg BW and above: Target Hb = 13 g/dl and storage iron = 15 mg/kg BW David McAuley, Pharm.D. 1) Ganzoni AM. Use Caution/Monitor. Interaction only with oral iron administration.

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